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CIRS Science
Consensus Statements
- Berndtson, K., McMahon, S., Ackerley, M., Rapaport, S., Gupta, S. & Shoemaker, R.C. (2015). Medically sound investigation and remediation of water-damaged buildings in cases of CIRS-WDB – Consensus statement – Pt 1. Center for research on biotoxin associated illnesses. Full text.
- Schwartz, L., Weatherman, G., Schrantz, M., Spakes, W., Charlton, J., Berndtson, K. & Shoemaker, R. (2016). Indoor environmental professionals panel of surviving mold – consensus statement. Full text.
Peer Reviewed Journal Papers
- Shoemaker, R.C. (2020). Metabolism, molecular hypometabolism and inflammation: Complications of proliferative physiology include metabolic acidosis, pulmonary hypertension, T reg cell deficiency, insulin resistance and neuronal injury. Trends diabetes metab., 3,1-15. Full text
- Shoemaker, R.C. & Lark, D. (2019). Urinary Mycotoxins: A Review of Contaminated Buildings and Food in Search of a Biomarker Separating Sick Patients from Controls. Internal medicine review, 5(6). Abstract | Full text | Townsend letter #438
- Shoemaker, R.C., Heyman, A., Mancia, A. & Ryan, J.C. (2017). Inflammation Induced Chronic Fatiguing Illnesses: A steady march towards understanding mechanisms and identifying new biomarkers and therapies. Internal Medicine Review, (3)10. doi: 10.18103/imr.v3i10.585 | Full text
- McMahon, S, Kundomal, K. & Yangalasetty, S. (2017). Pediatrics Norms for Visual Contrast Sensitivity Using an APT VCS Tester. Medical research archives, 5(5) May 2017. doi: 10.18103/mra.v5i5.1295 | Full text
- McMahon, S. (2017). An Evaluation of Alternate Means to Diagnose Chronic Inflammatory Response Syndrome and Determine Prevalence. Medical research archives, 5(3), March 2017. doi: 10.18103/mra.v5i3.1125 | Full text
- Shoemaker, R., Katz, D., Ackerley, M., Rapaport, S., McMahon, S., Berndtson, K. & Ryan, J. (2017). Intranasal VIP safely restores volume to multiple grey matter nuclei in patients with CIRS. Internal medicine review, (3)4. doi:10.18103/imr.v3i4.412 | Full text
- Ryan, J.C. & Shoemaker. R.C. (2016). RNA-Seq on patients with chronic inflammatory response syndrome (CIRS) treated with vasoactive intestinal peptide (VIP) shows a shift in metabolic state and innate immune functions that coincide with healing. Medical research archives, 4(7). 10.18103/mra.v4i7.862 | Full text
- Gunn, S.R., Gunn, G.G. & Mueller, F.W. (2016). Reversal of refractory ulcerative colitis and severe chronic fatigue syndrome symptoms arising from immune disturbance in an HLA-DR/DQ genetically susceptible individual with multiple biotoxin exposures. American journal of case reports, 2016(17), 320–325. doi: 10.12659/AJCR.896949 PMC4913732 PMID 27165859
- McMahon, S.W., Shoemaker, R.C. & Ryan, J.C. (2016). Reduction in forebrain parenchymal and cortical grey matter swelling across treatment groups in patients with inflammatory illness acquired following exposure to water-damaged buildings. Journal of neuroscience and clinical research, 2016, 1(1). doi: 10.4172/jnscr.1000102 | Full text
- Bredesen D.E. (2016). Inhalational Alzheimer’s disease: an unrecognized – and treatable – epidemic. Aging, 8(2), 304-13. doi: 10.18632/aging.100896 | PMID 26870879
- Ryan, J.C., Wu, Q., & Shoemaker, R.C. (2015). Transcriptomic signatures in whole blood of patients who acquire a chronic inflammatory response syndrome (CIRS) following an exposure to the marine toxin ciguatoxin. BMC med genomics, 2015, (8)15. doi: 10.1186/s12920-015-0089-x | PMID 25889530
- Shoemaker, R.C., House, D.E., & Ryan, J.C. (2014). Structural brain abnormalities in patients with inflammatory illness acquired following exposure to water-damaged buildings: A volumetric MRI study using NeuroQuant. Neurotoxicology and teratology, 45, 18-26. doi: 10.1016/j.ntt.2014.06.004 | PMID 24946038 | Full text
- Shoemaker, R.C., House, D.E., & Ryan, J.C. (2013). Vasoactive intestinal polypeptide (VIP) corrects chronic inflammatory response syndrome (CIRS) acquired following exposure to water-damaged buildings. Health, 5(3) 2013, 396-401. doi: 10.4236/health.2013.53053
- Shoemaker, R.C., House, D.E., & Ryan, J.C. (2010). Defining the neurotoxin derived illness chronic ciguatera using markers of chronic systemic inflammatory disturbances: a case/control study. Neurotoxicology and teratology, 32(6), 633-9. doi: 10.1016/j.ntt.2010.05.007 | PMID 20685390 | Full text
- Shoemaker, R.C., Giclas, P, Crowder, C, House, D.E., & Glovsky, M. (2008). Complement split products C3a and C4a are early markers of acute lyme disease in tick bite patients in the United States. International archives of allergy and immunology, 146(3), 255-61. doi: 10.1159/000116362 | PMID 18270493 | Full text
- Shoemaker, R.C., Hudnell, H.K., House, D.E., Van Kempen, A., & Pakes, G. (2006). Atovaquone plus cholestyramine in patients coinfected with Babesia microti and Borrelia burgdorferi refractory to other treatment. Advances in therapy, 23(1), 1-11. PMID 16644602 | Full text
- Shoemaker, R.C., & House, D.E. (2006). Sick building syndrome (SBS) and exposure to water-damaged buildings: time series study, clinical trial and mechanisms. Neurotoxicology and teratology, 28(5), 573-88. PMID 17010568 | Full text
- Hudnell, H.K. (2005). Chronic biotoxin-associated illness: multiple-system symptoms, a vision deficit, and effective treatment. Neurotoxicology and teratology, 27(5), 733-43. PMID: 16102938
- Shoemaker, R.C. & House, D.E. (2004). A time-series study of sick building syndrome: chronic, biotoxin-associated illness from exposure to water-damaged buildings. Neurotoxicology and teratology, 27(1), 29-46. PMID 15681119 | Full text
- Shoemaker, R.C. (2001). Residential and recreational acquisition of possible estuary-associated syndrome: a new approach to successful diagnosis and treatment. Environmental health perspectives, 109 (suppl. 5), 791-6. PMID PMC1240613
Peer Reviewed Conference Presentations
- Shoemaker, R., McMahon, S., Ryan, J., Ackerley, M., DiTulio, M., Berndtson, B., Heyman, A. & Jaffe, R. (2015). Correlation of volumetric brain imaging with Western blot testing for Lyme Disease. Poster session. NorVect conference, 2015. Summary
- Shoemaker, R.C. & Maizel, M. (2008). Innate immunity, MR spectroscopy, HLA DR, TGF beta-1, VIP and capillary hypoperfusion define acute and chronic human illness acquired following exposure to water-damaged buildings. International healthy buildings. Full text
- Shoemaker, R.C., Hudnell K.H., House, D.E. & Domenico, P. (2003). Association of nasal carriage of methicillin resistant and multiple antibiotic resistant coagulase negative staphylococci species with deficiency of alpha melanocyte stimulating hormone in Chronic Fatigue Syndrome: implication for expanded treatment options. American society of microbiology, 2003. Full text
- Shoemaker, R.C. (2003). Linkage disequilibrium in alleles of HLA DR: differential association with susceptibility to chronic illness following exposure to biologically produced neurotoxins. American society of microbiology. 2003. Full text
Non-peer reviewed
- Shaw, W. & Pratt-Hyatt, M. (2019). Biochemical Markers in the Urine Associated with Gastrointestinal Mold-Overgrowth Are Linked with Elevated Urinary Mycotoxins in Patients with Suspected Mold Illness. Townsend letter, #436. Full text.
- Shoemaker, R.C., Lark, D. & Ryan, J.C. (2019). Moldy Buildings, CIRS, Sick People, and Damaged Brains, Parts 1-5. Townsend letter, #432 Part 1, #433 Part 2, #435 Part 3, #436 Part 4, #437 Part 5
- Shoemaker, R.C. & Maziel, M.S. (2009). Exposure to interior environments of water-damaged buildings causes a CFS-like illness in pediatric patients: a case/control study. Bulletin of the IACFS/ME 2009, 17(2). Full text
- Shoemaker, S., Rash, J. & Simon, E. (2003). Sick building syndrome in water damaged buildings: generalization of the chronic biotoxin-associated illness paradigm to indoor toxigenic-fungi exposure. Bioaerosols, fungi, bacteria, mycotoxins and human health. Johanning, E (editor). Chapter Text
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